Stevens–Johnson syndrome complicated by pneumomediastinum and cerebral venous sinus thrombosis in a 10-year-old girl: A case Report

Pawan Jain; Rakesh Singh; Shriyanka Jain; Ankur Saxena; Ujjwala Verma; Vikash Kumar Bhojasiya

doi:10.4103/jpcc.jpcc_57_21

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CASE REPORT

Year : 2021 \| Volume : 8 \| Issue : 6 \| Page : 291-294

Stevens–Johnson syndrome complicated by pneumomediastinum and cerebral venous sinus thrombosis in a 10-year-old girl: A case Report Pawan Jain¹, Rakesh Singh¹, Shriyanka Jain², Ankur Saxena³, Ujjwala Verma⁴, Vikash Kumar Bhojasiya⁵ ¹ Department of Pediatrics, Ramkrishna CARE Hospital, Raipur, Chhattisgarh, India ² Department of Rheumatology, Ramkrishna CARE Hospital, Raipur, Chhattisgarh, India ³ Division of Cornea, Shri Aurobindo Nethralaya Hospital, Raipur, Chhattisgarh, India ⁴ Department of Dermatology, Ramkrishna CARE Hospital, Raipur, Chhattisgarh, India ⁵ Department of Radiodiagnosis, Ramkrishna CARE Hospital, Raipur, Chhattisgarh, India Correspondence Address: Dr. Pawan Jain Department of Pediatrics, Ramakrishna CARE Hospital, Aurobindo Enclave, Pachpedi Naka, Dhamtari Road, NH – 43, Raipur - 492 001, Chhattisgarh India Source of Support: None, Conflict of Interest: None DOI: 10.4103/jpcc.jpcc_57_21

Stevens–Johnson syndrome (SJS) is a life-threatening condition with severe mucocutaneous reaction in response to an offending medication. We report a case of SJS complicated with pneumomediastinum and cerebral sinus venous thrombosis in a girl. These two complications occurring simultaneously in a pediatric patient with SJS are hitherto unreported. Laboratory workup pointed underlying connective tissue disease in her. She received supportive care along with steroids, antimicrobials, and anticoagulant under supervision of a multidisciplinary team. She recovered well at discharge and is on follow-up. Clinical vigilance identifies rare but important complications of SJS early, mitigating severe morbidity and mortality.



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