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CASE SERIES
Year : 2022  |  Volume : 9  |  Issue : 3  |  Page : 100-103

Overlap of severe dengue with multisystem inflammatory syndrome in children due to SARS-CoV-2 infection: A case series from a tertiary care center of Central India


1 Department of PICU, Ankura Hospitals for Women and Children, Hyderabad, Telangana, India
2 Department of Pediatrics, MRIMS, Hyderabad, Telangana, India
3 Department of PICU and Pediatrics, Ankura Hospitals for Women and Children, Hyderabad, Telangana, India

Correspondence Address:
Dr. Krishna Chaitanya
Department of PICU, Ankura Children's Hospital, LB Nagar, Hyderabad - 500 074, Telangana
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpcc.jpcc_12_22

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India is currently facing a double burden of severe dengue and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Co-infection/complication due to these viruses can result in severe morbidity. We present five cases of severe dengue with multisystem inflammatory syndrome in children (MIS-C) due to SARS-CoV-2 infection in children. All children presented with shock with variable degrees of plasma leakage. They were treated initially as severe dengue cases; however, due to refractory symptoms such as persistent fever and inotropic requirement, an alternate diagnosis was suspected and established. They were successfully managed according to the World Health Organization Dengue Shock Syndrome and MIS-C Guidelines with intravenous (IV) fluids, methylprednisolone, aspirin, and IV immunoglobulin. Severe dengue in endemic regions overlapping with MIS-C makes it difficult to diagnose which needs early recognition and appropriate management.


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