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ORIGINAL ARTICLE
Year : 2022  |  Volume : 9  |  Issue : 4  |  Page : 124-130

Outbreak of respiratory syncytial virus infection in Eastern India during COVID-19 pandemic: An observational study from a single pediatric intensive care unit


1 Department of Pediatrics, Medical College and Hospital, Kolkata, West Bengal, India
2 Department of Pediatrics, North Bengal Medical College and Hospital, Siliguri, West Bengal, India

Correspondence Address:
Dr. Manas Kumar Mahapatra
Doctors Chummery Hostel, 41 Eden Hospital Road, Kolkata - 700 073, West Bengal
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jpcc.jpcc_27_22

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Background: After the peak of the second wave of COVID-19 pandemic, we faced a surge of respiratory syncytial virus (RSV) infection. This study was aimed to estimate the severity, clinical course, and outcome of RSV-infected children admitted in pediatric intensive care unit and to identify the predictors of development of acute respiratory distress syndrome (ARDS). Subjects and Methods: This retrospective study included children below 5 years with influenza-like illnesses (ILI) due to RSV infection. The clinical, laboratory, treatment, and outcome-related parameters were assessed and a compared between ARDS and non-ARDS group. Results: Out of 44 ILI patients, 36 had RSV infection. Most of them (88.9%) were infants. Twenty-four (66.7%) patients developed ARDS and 9 (25%) were ventilated. Infants below 6 months, low birth weight (LBW) babies, consolidations (≥3 zones), interstitial edema (≥3 zones) in lung ultrasound, high pediatric sequential organ failure assessment (pSOFA), and Pediatric Risk of Mortality III score were significantly associated with ARDS. Conclusions: RSV-infected children with young age (1–6 months), LBW, higher lung ultrasound, and pSOFA score should alert physicians for progression to ARDS.


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