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| ORIGINAL RESEARCH ARTICLES |
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| The impact of mannitol administration in pediatric DKA: A 22 year experience
William E Novotny, Glenn D Harris, Irma Fiordalisi, Suzanne Hudson, Ronald M Perkin
October-December 2015, 2(4):37-44
DOI:10.21304/2015.0204.00094
Objective: To describe circumstances and outcomes associated with mannitol administration in children being treated for diabetic ketoacidosis (DKA).
Design: Retrospective chart review of consecutively admitted pediatric patients over a 22 year period (1988-2010).
Setting: Data originate from three pediatric tertiary care centers where DKA was routinely treated during the study period with a physiologic approach to gradual rehydration, continuous IV insulin and intensive monitoring for symptomatic brain swelling. Mannitol was the drug of choice for suspected raised intracranial pressure (ICP).
Patients: 941 consecutive patient episodes of moderate to severe DKA were reviewed for mannitol administration.
Interventions: None
Measurements and Main Results: Mannitol was administered during 76 of 941 episodes of DKA. Mannitol was successful 111 improving 01- reversing signs/symptoms of raised ICP 111 65% of mannitol recipients. No patient 111 this series suffered neurologic morbidity of mortality.
Conclusions: Mannitol treatment for suspected raised ICP during treatment for DICA appears to be safe and beneficial to outcome when combined with careful rehydration, continuous insulin therapy, and cerebrovascular and biochemical monitoring.
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| 901 | 69 | - |
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| CASE REPORTS |
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| Acute myocardial infarction in a patient of infective endocarditis
Prabhas Prasun Giri, Säumen Meur, Salini Sikka
October-December 2015, 2(4):51-53
DOI:10.21304/2015.0204.00097
Infective endocarditis (IE) is associated with a number of complications. Peripheral systemic embolism is a common and serious complication of infective endocarditis linked to migration of vegetation. Here we present a case of a 9 year old girl admitted with left hemiplegia due to right MCA thromboemobolism due to naïve aortic valve IE and ultimately expired due to an acute coronary syndrome (ACS) due to possible coronary embolism.
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| 870 | 51 | - |
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| CLINICAL REVIEW |
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| Viscoelastic hemostatic assays
Anil Sachdev, Sandeep Dhingra
October-December 2015, 2(4):63-70
DOI:10.21304/2015.0204.00101
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| 860 | 45 | - |
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| ORIGINAL RESEARCH ARTICLES |
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| Stress level amongst parents of Neonatal Intensive Care Unit (NICU) graduates vs parents of pediatric intensive care unit (picu) graduates in rural teaching hospital - A comparative study
Parthavi Patel, Prasad Muley, Maitray patel
October-December 2015, 2(4):45-47
DOI:10.21304/2015.0204.00095
Objective: To compare the stress amongst parents whose babies were admitted in NICU with that of the parents of children admitted in PICU
Methods: Prospective study conducted at a tertiary level hospital with well equipped NICU and PICU. Eligible parent’s (both mother and father) stress level was analyzed with the help of Parental Stress Scale (PSS).
Results: Total 120 participants (mother and father) with 60 from each group were subjected to PSS. Mean score of fathers and mothers whose children were admitted to PICU had more stress as compared to those in NICU (p-value <0.001). Similarly stress was more in less educated (p-value<0.005) and low income group (p-value <0.01) parents.
Conclusion: Our study concludes that guardians of children admitted to PICU have more Stress compared to that of neonates admitted in NICU and stress is negatively related with their educational qualification, income and number of children.
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| 827 | 52 | - |
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| SYMPOSIUMS |
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| Optimising the dosing of antibiotics: Colistin and vancomycin updates
Reklia Solomon, Soumya Thambi, Soonu Udani
October-December 2015, 2(4):24-32
DOI:10.21304/2015.0204.00092
Multidrug resistant gram-negative nosocomial infection in intensive care units has resulted in an increased use of antibiotics like Colistin and Tigeicycline that the end user may have little experience with. Mechanism of drug resistance, when understood, leads to the correct choice and combination of antibiotics. Understanding the phamacokinetics of Colistin and proper dosing with a correct loading dose is vital to treatment success. Issues regarding renal toxicity may be important factors in critically ill children and much of the dosing is extrapolated form adult studies.
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| 763 | 48 | - |
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| CRITICAL THINKING |
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| PICU Quiz
Praveen Kliilnani
October-December 2015, 2(4):61-62
DOI:10.21304/2015.0204.00100
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| 706 | 104 | - |
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| SYMPOSIUMS |
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| The central venous catheter: Life line or hangman s noose?
Soonu Udani
October-December 2015, 2(4):15-20
DOI:10.21304/2015.0204.00090 |
| 709 | 59 | - |
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| CASE REPORTS |
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| Congenital laryngotracheoesophageal cleft masquerading as recurrent pneumonia
Vishrutha , H Ramesh, M Mohan, BM Harsha
October-December 2015, 2(4):48-50
DOI:10.21304/2015.0204.00096
Laryngotracheoesophageal cleft (LTEC) is a uncommon congenital malformation of the posterior part of the larynx, creating an abnormal communication between the laryngotracheal axis and the pharyngo- oesophageal axis. Tins condition manifest with non-specific respiratory symptoms, posing diagnostic challenge. Here we report a case of 75 days old infant with recurrent pneumonia and acute life threatening event manifested as milk aspiration. On endoscopic evaluation type 1 LTEC (Laryngeo trachea esophageal cleft) was diagnosed. Intervention/Outcome : Infant was managed conservatively and doing well on follow up.
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| 729 | 37 | - |
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| Unusual cause of renal failure in infancy: Primary hyperoxaluria
Kanchan Channawar, VS V Prasad
October-December 2015, 2(4):54-56
DOI:10.21304/2015.0204.00098
Background: Primary hyperoxaluria is a rare disease characterized by the excessive production and accumulation of oxalate in the body.
Methods: We described the case of an infant with primary hyperoxaluria type who had end-stage renal failure in the second month of life, family history of deaths due to renal disease, renal biopsy showing intense deposition of oxalate crystals 111 the lumen, tubular cells, and kidney interstitium, with secondary glomerular disorder.
Conclusions: primary hyperoxaluria type I should be regarded as one of the differential diagnoses of renal failure in the first months of life, especially when no suggestive history of other diseases is present
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| 704 | 47 | - |
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| SYMPOSIUMS |
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| The role of vitamin D in sepsis: A review
Soonu Udani
October-December 2015, 2(4):33-36
DOI:10.21304/2015.0204.00093 |
| 683 | 52 | - |
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| The endothelial glycocalyx and sepsis
Ashit Hegde
October-December 2015, 2(4):21-23
DOI:10.21304/2015.0204.00091 |
| 681 | 47 | - |
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| BEST EVIDENCE |
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| Journal scan
Anil Sachdev
October-December 2015, 2(4):57-60
DOI:10.21304/2015.0204.00099 |
| 649 | 54 | - |
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| SYMPOSIUMS |
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| Ventilator associated events: Deconstructing a new algorithm
Soonu Udani, Rekha Solomon
October-December 2015, 2(4):9-14
DOI:10.21304/2015.0204.00089 |
| 591 | 58 | - |
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| SYNOPSIS BY ILCOR PEDIATRIC TASK FORCES |
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| Pediatric advanced life support (PALS) 2015 update
October-December 2015, 2(4):71-81 |
| 587 | 47 | - |
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| A SYNOPSIS BY ILCOR PEDIATRIC TASK FORCES |
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| Pediatrie basic life support, pediatrie advanced life support and neonatal resuscitation 2015
October-December 2015, 2(4):82-89 |
| 577 | 43 | - |
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| SYMPOSIUMS |
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| Guest editorial: Symposium “infections in the PICU- A side view”
Soonu Udani
October-December 2015, 2(4):7-8
DOI:10.21304/2015.0204.00088 |
| 554 | 46 | - |
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